THE LANCET - The effect of frailty on survival in patients with COVID-19 (COPE): a multicentre, European, observational cohort study

THE LANCET - The effect of frailty on survival in patients with COVID-19 (COPE): a multicentre, European, observational cohort study

The COVID-19 pandemic has placed unprecedented strain on health-care systems. Frailty is being used in clinical decision making for patients with COVID-19, yet the prevalence and effect of frailty in people with COVID-19 is not known. In the...
NEJM - Accelerating Development of SARS-CoV-2 Vaccines — The Role for Controlled Human Infection Models

NEJM - Accelerating Development of SARS-CoV-2 Vaccines — The Role for Controlled Human Infection Models

The New England Journal of MedicineThe third coronavirus outbreak in the past 20 years, the SARS-CoV-2 pandemic has caused unprecedented morbidity, mortality, and economic disruption. Safe, effective, and deployable SARS-CoV-2 vaccines are...
SCIENCE - A mathematical model reveals the influence of population heterogeneity on herd immunity do SARS-CoV-2

SCIENCE - A mathematical model reveals the influence of population heterogeneity on herd immunity do SARS-CoV-2

Despite vairious levels of preventive measures, in 2020 many countries have suffered severely from coronavirus 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus.

NEJM - Multisystem Inflammatory Syndrome in U.S. Children and Adolescents

NEJM - Multisystem Inflammatory Syndrome in U.S. Children and Adolescents

The New England Journal of MedicineUnderstanding the epidemiology and clinical course of multisystem inflammatory syndrome in children (MIS-C) and its temporal association with coronavirus disease 2019 (Covid-19) is important, given the clinical...
JAMA - Clinical Characteristics and Outcomes in Patients With Coronavirus Disease 2019 and Multiple Sclerosis

JAMA - Clinical Characteristics and Outcomes in Patients With Coronavirus Disease 2019 and Multiple Sclerosis

JAMA NETWORK

What are the risk factors for developing a severe form of coronavirus disease 2019 (COVID-19) in patients with multiple sclerosis (MS)?

THE LANCET - COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study

THE LANCET - COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study

To date, few data on paediatric COVID-19 have been published, and most reports originate from China. This study aimed to capture key data on children and adolescents with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection...
THE LANCET - Tocilizumab in patients with severe COVID-19: a retrospective cohort study

THE LANCET - Tocilizumab in patients with severe COVID-19: a retrospective cohort study

No therapy is approved for COVID-19 pneumonia. The aim of this study was to assess the role of tocilizumab in reducing the risk of invasive mechanical ventilation and death in patients with severe COVID-19 pneumonia who received standard of care...
THE LANCET - Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study

THE LANCET - Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study

Comprehensive characterisation of clinical syndromes is crucial to allow rational selection and evaluation of potential therapies. The aim of this study was to investigate the breadth of complications of COVID-19 across the UK that affected the...
JAMA - Evaluation of Chilblains as a Manifestation of the COVID-19 Pandemic

JAMA - Evaluation of Chilblains as a Manifestation of the COVID-19 Pandemic

JAMA Network

Is there an association between chilblains and coronavirus disease 2019 (COVID-19)?

CDC updates, expands list of people at risk of severe COVID-19 illness

CDC updates, expands list of people at risk of severe COVID-19 illness

Centers for Disease Control and PreventionBased on a detailed review of available evidence to date, CDC has updated and expanded the list of who is at increased risk for getting severely ill from COVID-19.
NASEM - A Guide for Decision Makers using Data to Understand the Extent and Spread of COVID-19

NASEM - A Guide for Decision Makers using Data to Understand the Extent and Spread of COVID-19

The National Academies of Sciences Engineering Medicine - SEANThis rapid expert consultation was peoduced trough the Societal Experts Action Network (SEAN), an activity of The National Academies of Sciences, Engineering and Medicine that is...
WHO - Breastfeeding and COVID-19

WHO - Breastfeeding and COVID-19

World Health OrganizationBreastfeeding is the cornerstone of infant and young child survival, nutrition and development and maternal health. The World Health Organization recommends exclusive breastfeeding for the first 6 months of life, followed...
ECDC - Heating, ventilation and air-conditioning systems in the context of COVID-19

ECDC - Heating, ventilation and air-conditioning systems in the context of COVID-19

European Centre for Disease Prevention and ControlEvidence for transmission in closed spaces and the role of heating, ventilation and air-conditioning (HVAC) systems Heating, ventilation and air-conditioning (HVAC) systems are used to provide...
THE LANCET - Seeing COVID-19 through José Saramago’s Blindness

THE LANCET - Seeing COVID-19 through José Saramago’s Blindness

Some 6 months into the COVID-19 pandemic, the emotional devastation, socioeconomic impacts, and pressures on front-line health-care workers continue to shape our world. While words cannot always do justice to the extent of individual suffering...
THE LANCET - Feasibility and physiological effects of prone positioning in non-intubated patients with acute respiratory failure due to COVID-19 (PRON-COVID): a prospective cohort study

THE LANCET - Feasibility and physiological effects of prone positioning in non-intubated patients with acute respiratory failure due to COVID-19 (PRON-COVID): a prospective cohort study

The COVID-19 pandemic is challenging advanced health systems, which are dealing with an overwhelming number of patients in need of intensive care for respiratory failure, often requiring intubation. Prone positioning in intubated patients is...
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