Imagiologia e clínica

ECDC - Reinfection with SARS-CoV-2: implementation of a surveillance case definition within the EU/EEA

European Centre for Disease Prevention and ControlReinfection with SARS-CoV-2 has been reported both within the European Union/European Economic Area (EU/EEA) and globally. This report summarises the available evidence about reinfection and...

AMP - Obesity and COVID-19: Present and Future

Acta Médica PortuguesaCom a chegada da COVID-19 à Europa e depois aos Estados Unidos, começou a avolumar-se a evidência que apontava a obesidade como uma das principais comorbilidades associadas a doença grave por COVID-19. Um dos primeiros...

AMP - Abordagem da Cefaleia no Doente com COVID-19

Acta Médica PortuguesaHeadache is one of the most common neurological symptoms of COVID-19. It has an estimated prevalence of 6% to 71% with most studies reporting 6% to 21%. It often appears simultaneously with other COVID-19 symptoms, is...

JAMA - Four-Month Clinical Status of a Cohort of Patients After Hospitalization for COVID-19

JAMA NETWORK

This study provides clinical status of a cohort of patients 4 months after hospitalization for COVID-19, but further research is needed to understand longer-term outcomes.

WHO - COVID-19 Clinical management: living guidance

World Health OrganizationProviding trustworthy guidance that is comprehensive and holistic for the optimal care of COVID-19 patients, throughout their entire illness is necessary. The previous version of the Clinical management of COVID-19...

NICE - COVID-19 rapid guideline: managing the long-term effects of COVID-19

National Institute for Health and Care ExcellenceThis guideline covers identifying, assessing and managing the long-term effects of COVID-19, often described as ‘long COVID’. It makes recommendations about care in all healthcare settings for...

AMP - Cutaneous Manifestations Associated with COVID-19: A Narrative Review

Acta Médica PortuguesaCOVID-19 is an infectious disease caused by the new coronavirus, SARS-CoV-2, that has spread rapidly throughout the world. This has resulted in an urgent need to obtain information regarding its pathogenesis, diagnosis and...

AMP - Manifestações Neurológicas e COVID-19

Acta Médica PortuguesaO advento da pandemia da COVID-19 despertou interesse da comunidade científica sobre o possível neurotropismo do SARS-CoV-2 e da extensão do seu potencial dano direto e/ou indireto no sistema nervoso. Um crescente número de...

THE LANCET - Scientific consensus on the COVID-19 pandemic: we need to act now

The LancetSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 35 million people globally, with more than 1 million deaths recorded by WHO as of Oct 12, 2020. As a second wave of COVID-19 affects Europe,...

THE LANCET - Genomic evidence for reinfection with SARS-CoV-2: a case study

The LancetThe degree of protective immunity conferred by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently unknown. As such, the possibility of reinfection with SARS-CoV-2 is not well understood. We describe...

NEJM - Humoral Immune Response to SARS-CoV-2 in Iceland

The New England Journal of MedicineOf the 1797 persons who had recovered from SARS-CoV-2 infection, 1107 of the 1215 who were tested (91.1%) were seropositive; antiviral antibody titers assayed by two pan-Ig assays increased during 2 months after...

NEJM - Saliva or Nasopharyngeal Swab Specimens for Detection of SARS-CoV-2

The New England Journal of MedicineRapid and accurate diagnostic tests are essential for controlling the ongoing Covid-19 pandemic. Although the current standard involves testing of nasopharyngeal swab specimens by quantitative...

NEJM - Rapid Decay of Anti–SARS-CoV-2 Antibodies in Persons with Mild Covid-19

The New England Journal of MedicineA recent article suggested the rapid decay of anti–SARS-CoV-2 IgG in early infection,1 but the rate was not described in detail. We evaluated persons who had recovered from Covid-19 and referred themselves...

JAMA - Thrombosis in Hospitalized Patients With COVID-19 in a New York City Health System

JAMA NETWORKPatients with coronavirus disease 2019 (COVID-19) are at increased risk of thrombosis. However, studies have been limited in size, did not report all thrombotic events, and focused on patients with severe disease hospitalized in...

JAMA - Factors Associated With Death in Critically Ill Patients With Coronavirus Disease 2019 in the US

JAMA NetworkThis study identified demographic, clinical, and hospital-level factors associated with death in critically ill patients with COVID-19 that may be used to facilitate the identification of medications and supportive therapies that can...