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ECDC - Rollout of COVID-19 vaccines in the EU/EEA: challenges and good practice

European Centre for Disease Prevention and Control

This document outlines the key challenges that countries are facing with the COVID-19 vaccination rollout and lessons learned to mitigate these challenges.

ECDC - Risk of SARS-CoV-2 transmission from newly-infected individuals with documented previous infection or vaccination

European Centre for Disease Prevention and ControlMore than one year into the SARS-CoV-2 pandemic, over 120 million people have been infected with the virus across more than 200 countries. Reinfections following natural infections with the same...

AMP - The Impact of the COVID-19 Pandemic on Children’s Health in Portugal: The Parental Perspective

Acta Médica PortuguesaThe COVID-19 pandemic poses unprecedented challenges for healthcare services and has led to changes in the usage pattern of the pediatric population. We aimed to describe the impact of COVID-19 on children’s health,...

JAMA - Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted

JAMA NETWORK

The results do not support routine empirical use of intermediate-dose prophylactic anticoagulation in unselected patients with COVID-19 admitted to the ICU.

AMP - Abordagem da Cefaleia no Doente com COVID-19

Acta Médica PortuguesaHeadache is one of the most common neurological symptoms of COVID-19. It has an estimated prevalence of 6% to 71% with most studies reporting 6% to 21%. It often appears simultaneously with other COVID-19 symptoms, is...

JAMA - Four-Month Clinical Status of a Cohort of Patients After Hospitalization for COVID-19

JAMA NETWORK

This study provides clinical status of a cohort of patients 4 months after hospitalization for COVID-19, but further research is needed to understand longer-term outcomes.

ECDC - Introducing a coherent European framework for tuning COVID-19 response measures

European Centre for Disease Prevention and ControlThis document describes the development of a coherent, yet non-prescriptive framework for tuning COVID-19 response measures in the European Union and European Economic Area (EU/EEA). Its aim is to...

ECDC - Considerations on the use of self-tests for COVID-19 in the EU/EEA

European Centre for Disease Prevention and ControlRapid antigen detection tests (RADTs) that can be used as self-tests to detect SARS-CoV-2 are becoming available in the European Union/European Economic Area (EU/EEA). These tests require...

ECDC - Guidance for COVID-19 quarantine and testing of travellers

European Centre for Disease Prevention and ControlTravel measures, such as quarantine and testing of travellers, are designed to reduce the likelihood of SARS-CoV2 transmission prior to, during, and after travel. This document summarises the...

JAMA - SARS-CoV-2 Vaccines

JAMA NETWORKShortly after SARS-CoV emerged at the turn of the 21st century, the spike (S) protein (particularly in its prefusion [native] conformation) was identified as the immunodominant antigen of the virus. Evaluation of patients with...

JAMA - Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19A Systematic Review and Meta-analysis

JAMA NETWORKIn a meta-analysis of 4 peer-reviewed and published randomized clinical trials including 1060 patients with COVID-19 treated with convalescent plasma vs control, the risk ratio for mortality was 0.93 and after the addition of 6...

NEJM - BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Mass Vaccination Setting

The New England Journal of MedicineAs mass vaccination campaigns against coronavirus disease 2019 (Covid-19) commence worldwide, vaccine effectiveness needs to be assessed for a range of outcomes across diverse populations in a noncontrolled...

JAMA - Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19

JAMA NETWORKHow do the characteristics and outcomes of children and adolescents with multisystem inflammatory syndrome in children (MIS-C) compare with severe coronavirus disease 2019 (COVID-19)?

CDC - Operating schools during COVID-19: CDC's Considerations

Centre for Disease Prevention and ControlAs communities in the United States consider how to safely re-open K-12 school buildings for in-person learning and activities and keep them open, CDC offers updated considerations for mitigation...

ECDC - Detection and characterisation capability and capacity for SARS-CoV-2 variants within the EU/EEA

European Centre for Disease Prevention and ControlECDC’s rapid risk assessment on the spread of new SARS-CoV-2 variants of concern in the EU/EEA, published on 21 January 2021, concludes that the risk associated with the introduction and community...